Pain in Charcot-Marie-Tooth disease: an update

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Update on Charcot-Marie-Tooth disease.

PURPOSE OF REVIEW Charcot-Marie-Tooth disease (CMT) is the common terminology used to describe the hereditary neuropathies. This update reviews advances in the past year in our understanding of these diseases, including some important earlier references. RECENT FINDINGS In the past year, advances in next-generation sequencing continued to increase the number of genes associated with CMT. The ...

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How far away is an effective therapy for Charcot-Marie-Tooth disease (CMT), the most frequent inherited neuropathy affecting approximately one individual in every 2500 around the world [1]? The next few years will be fundamental to giving the answer to this key question about a still untreatable disorder, for which rehabilitation therapy and surgical correction of skeletal deformities still rep...

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Charcot-Marie-Tooth (CMT) disease is the most prevalent peripheral inherited neuropathy (1/2500 to 10 000; 2.8/10 000 in Spain), and the mean age at onset is 16 years (range 2 to 50 years, but presentation in the early infancy and as late as the 80's has been reported). Patients present with motor and sensory polyneuropathic semiology (distal lower limb weakness and atrophy, gait abnormalities ...

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Charcot-Marie-Tooth (CMT) disease is the most prevalent peripheral inherited neuropathy (1/2500 to 10 000; 2.8/10 000 in Spain), and the mean age at onset is 16 years (range 2 to 50 years, but presentation in the early infancy and as late as the 80's has been reported). Patients present with motor and sensory polyneuropathic semiology (distal lower limb weakness and atrophy, gait abnormalities ...

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Background and aims: Charcot Marie Tooth disease (CMT) is the most prevalent hereditary neuropathy and its frequency is 1 in 2500. CMT is a heterogeneous disease and has different clinical symptoms. The prevalence of CMT and involved genes differ in different countries. CMT patients experience considerable sleep problems and a higher risk of decreased quality of life. In this w...

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ژورنال

عنوان ژورنال: Arquivos de Neuro-Psiquiatria

سال: 2018

ISSN: 1678-4227,0004-282X

DOI: 10.1590/0004-282x20180021